Archive for October 18, 2007

University of Manchester Developing Bionic Nerves

Research on artificial nerve grafting for treatment of patients with traumatic injuries of nerves in the arms and legs, organ transplants and the removal of tumors:

University of Manchester researchers have transformed fat tissue stem cells into nerve cells — and now plan to develop an artificial nerve that will bring damaged limbs and organs back to life.

In a study published in October’s Experimental Neurology, Dr Paul Kingham and his team at the UK Centre for Tissue Regeneration (UKCTR) isolated the stem cells from the fat tissue of adult animals and differentiated them into nerve cells to be used for repair and regeneration of injured nerves. They are now about to start a trial extracting stem cells from fat tissue of volunteer adult patients, in order to compare in the laboratory human and animal stem cells. [via University of Manchester]

Brain Games and Cognitive Reserve

Scientists studing “cognitive reserve” [resources for withstanding brain aging], are seeking methods for improving brain health:

Physical exercise is the best-proven prescription so far, the scientists agreed. Memory improved when 72-year-olds started a walking program three days a week, and sophisticated scans showed their brains’ activity patterns started resembling those of younger people…

Then there’s the “use-it-or-lose-it” theory, that people with higher education, more challenging occupations and enriched social lives build more cognitive reserve than couch potatoes.

Everything from doing crossword puzzles to various computer-based brain-training programs has been touted, but nothing is yet proven to work [while] animal studies suggesting low-dose estrogen and drugs that might mimic or ramp up brain signaling are promising possibilities. [via Wired News]

Thinking In Our Blood [Literally]

MIT researchers believe that blood may actually play a role in neural activitiy:

“We hypothesize that blood actively modulates how neurons process information,” Christopher Moore, a principal investigator in the McGovern Institute for Brain Research at MIT, explained in an invited review in the October issue of the Journal of Neurophysiology. “Many lines of evidence suggest that blood does something more interesting than just delivering supplies. If it does modulate how neurons relay signals, that changes how we think the brain works.” [via MIT News]

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